If you are passionate about making a real difference in public health, the HIV/TB Project Investigator Jobs in Eswatini with Pact could be your next career move. Offering a salary of 90000 to 150000 USD per year (about L 1,565,000 to L 2,605,500 SZL), this full-time position in 2026 requires extensive experience in global health, particularly in HIV and TB programs.
This role is based physically in Eswatini, working closely with the Ministry of Health and international partners to strengthen systems and save lives.
Details:
- Title: HIV/TB Project Investigator Jobs in Eswatini
- Location: Eswatini
- Employer: Pact
- Job Nature: Evaluation, Audit and Oversight
- Category: Full-time
Employer Overview:
Pact is a global nonprofit organization operating in nearly 40 countries, developing solutions for human development that are grounded in evidence, driven by data, and led by the communities we serve. Established in 1971, Pact collaborates with partners to foster resilience, enhance accountability, and develop knowledge and skills to achieve sustainable social impact.
Position Details:
Pact is seeking an experienced Principal Investigator (PI) for the Centers for Disease Control and Prevention (CDC) to enhance the technical and organizational capacity of the Ministry of Health in the Kingdom of Eswatini. The objective is to establish an efficient, resilient, and self-reliant HIV/TB response and to address associated public health threats under the President’s Emergency Plan for AIDS Relief (PEPFAR).
This initiative aims to strengthen Eswatini’s response to HIV and TB by delivering targeted technical assistance to government institutions, with the goal of eliminating HIV as a public health threat. The support will enhance the Ministry of Health’s technical and organizational capabilities to ensure effective program leadership, oversight, planning, and coordination. This position is subject to the successful award.
Responsibilities of HIV/TB Project Investigator Jobs in Eswatini:
Responsibilities of HIV/TB Project Investigator Jobs in Eswatini given below:
- The Principal Investigator will offer comprehensive technical and administrative leadership and expertise for the project.
- They will be accountable for the comprehensive oversight and execution of the project and will act as the main point of contact with the CDC regarding management and technical issues.
- They will ensure that the project fulfills its specified objectives, outcomes, benchmarks, and reporting obligations.
- They will advocate for the adoption of established evidence-based tools and innovative approaches to enhance the capacities of local organizations.
- S/he will assume a leadership role in coordinating efforts among CDC and key stakeholders, including partners, government entities, and other CDC and donor-funded initiatives.
- They will oversee and coordinate the execution of activities among project participants, ensuring effective integration of all activities.
- They will coordinate closely with Pact’s Washington, DC, team to ensure that all project activities adhere to USG regulations and are aligned with Pact’s policies, procedures, and best practices.
- They will supervise project planning, including the development of work plans and project budgets, as well as monitoring and reporting, such as reviewing and approving periodic budgets and technical and financial reports, in accordance with the highest standards.
- They will be responsible for overseeing the project budget and collaborating closely with the Business Official to achieve the anticipated outcomes, ensuring the efficient utilization of donor and Pact’s resources.
- They will deliver strategic leadership and supervision of the project’s subaward portfolio.
- They will supervise project personnel in assisting partners to develop reporting and monitoring systems that deliver essential information in an efficient and timely fashion.
- They will ensure that the program achieves its objectives and financial targets while providing precise projections.
- They will serve as the project’s representative at conferences, working groups, and meetings to promote CDC and Pact’s thought leadership in HIV prevention, care, and treatment among vulnerable populations.

Basic Requirements:
- Master’s degree and over 11 years of pertinent experience or an equivalent mix of education and experience, including a minimum of 6 years in a management capacity.
- A minimum of 11 years of extensive experience in international health initiatives, with a focus on HIV, TB, capacity enhancement, service provision, and/or health systems strengthening.
- A minimum of eight years of professional experience as a Project Director or in an equivalent senior leadership and primary managerial role on international donor initiatives.
- Experience in Southern Africa, with a preference for Eswatini.
- Experience in managing and leading teams for US government contracts and/or cooperative agreements.
- Displayed strong leadership abilities.
- Knowledge of PEPFAR-funded program implementation and reporting obligations.
- Proven history of successfully establishing and efficiently overseeing a diverse team of employees and associates.
- Proven capability to operate effectively within complex environments and collaborate with various stakeholders.
- Capacity to establish and sustain robust relationships with government and community stakeholders.
- Exhibited expertise in analytical problem solving and consensus development.
- The candidate must demonstrate proficiency in English across speaking, writing, and reading skills.
- Capacity to travel within Eswatini and, on occasion, internationally.
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Preferred Qualifications:
- Understanding of the political, social, and economic environment of Eswatini.
- Comprehensive knowledge of public health, health systems, and health policy and practice in Eswatini, with particular emphasis on HIV.
- Experience collaborating with community-based organizations and/or marginalized groups in Eswatini.
- Eswatini citizens and permanent residents are invited to submit their applications.
Benefits of HIV/TB Project Investigator Jobs in Eswatini:
- Competitive Salary
Earn a strong salary of 90000 to 150000 USD per year, reflecting your expertise in global health leadership. - Full-Time Employment
Enjoy the security and stability of a full-time role with clearly defined responsibilities and impact. - Meaningful Work
Contribute directly to HIV and TB prevention and care, improving health outcomes for vulnerable communities. - Leadership Opportunity
Lead and manage international teams, shaping strategy and guiding project implementation. - Professional Development
Gain experience with CDC-funded programs, enhancing skills in program management, monitoring, and evaluation. - Networking
Work closely with government, NGOs, and international partners, expanding your professional connections. - Travel Opportunities
Occasional travel within Eswatini and internationally allows exposure to diverse health systems and practices. - Impactful Recognition
Represent the project at conferences and meetings, building your reputation as a thought leader in public health. - Organizational Support
Collaborate with Pact’s global team, ensuring adherence to best practices and access to valuable resources. - Contribution to Public Health
Play a key role in strengthening Eswatini’s health systems, leaving a lasting impact on communities and national health outcomes.
How to Apply for HIV/TB Project Investigator Jobs in Eswatini?
Conclusion:
The HIV/TB Project Investigator role in Eswatini offers a unique chance to lead critical public health initiatives and strengthen local health systems. With a focus on HIV and TB, it combines strategic leadership, technical expertise, and meaningful community impact. This position is ideal for experienced professionals eager to drive change and make a lasting difference in Eswatini’s health landscape.
Frequently Asked Questions:
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Can Eswatini nationals apply?
Yes, Eswatini citizens and permanent residents are encouraged to apply.
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What type of projects will I oversee?
You will manage HIV and TB prevention, treatment, and capacity-strengthening initiatives funded by the CDC and PEPFAR.
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Will I work directly with patients?
No, this role focuses on program leadership, technical support, and capacity building rather than direct patient care.